GLPG1790, a small molecule nanomolar inhibitor of ephrinand a few other tyrosine kinases, shows potent anti-tumor activity in vitro and in vivo in a mouse MDA-MB-231xenograft model.1 Here we report its effects on apoptosis and angiogenesis after 3 days of oral treatment using non-invasive in vivo fluorescence imaging. Correlation with immunohistology readouts was studied.
